
Harrison Shepherd, born in America and raised in Mexico, works as a cook in the household of Diego Rivera and Frida Kahlo and then as secretary to Leon Trotsky in exile.
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Daniel Isaacson, the son of a couple executed for spying in the 1950s, struggles in the late 1960s with their memory, his sister's breakdown and his own anger, in Doctorow's novel based on the Rosenberg case.

In 1946 Evelyn Sert, a twenty-year-old Jewish hairdresser from Soho, sails to Palestine and is caught up in Tel Aviv and the struggle for a new state.

The President nominates a controversial man for Secretary of State, and the Senate's confirmation fight drags the secrets of everyone involved into the open.
Edith Campbell Berry, an idealistic young Australian, works for the League of Nations and then for the new world order after the war.

Ruth Becker, an old woman in Sydney, remembers her youth in Berlin among the German left in the 1930s, and the exile in London with the playwright Ernst Toller and her cousin Dora.

In 1956 the CIA recruits Irina, a young Russian-American typist, to work alongside Sally, an experienced agent, on a plan to smuggle Boris Pasternak's banned Doctor Zhivago into the Soviet Union.
Lee Harvey Oswald drifts from the Bronx to the Marines to Minsk to Dallas while a group of disaffected CIA men plan a staged attempt on Kennedy that is meant to miss.

Anna Wulf, a blocked novelist in 1950s London, keeps four notebooks for the parts of her life, black for Africa, red for politics, yellow for fiction and blue for daily life, and tries to bring them together in a fifth.

In 1876 Maryna Zalezowska, Poland's greatest actress, leaves the stage and sails with her husband, her son and a few friends to found a utopian farm in California.

The housekeeper and cousin-in-law of a fading Victorian novelist becomes obsessed with the Tichborne trial, where a butcher claims to be a lost aristocrat and a formerly enslaved man testifies for him.

Leah, a writer, and Bernie, a photographer, meet through a Philadelphia housemate ad, and when Bernie's old professor leaves her a complicated inheritance the two set out across rural Pennsylvania to make a book of words and pictures.
The story of Lexington, the most celebrated racehorse in nineteenth-century America, and Jarret, the enslaved groom who raised him, connects to a 1950s New York art dealer and, in 2019, to a Smithsonian scientist and a Nigerian-American art historian who uncover their story.