
In 1913 Laura Lyons lives in an apartment inside the New York Public Library, where her husband is superintendent, and is drawn into a club of radical women. In 1993 her granddaughter Sadie, a curator there, faces a run of thefts of rare books.
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In 1956 the CIA recruits Irina, a young Russian-American typist, to work alongside Sally, an experienced agent, on a plan to smuggle Boris Pasternak's banned Doctor Zhivago into the Soviet Union.

In 1791 Nella runs a hidden London apothecary selling poisons to women who want rid of the men who wronged them, and two centuries later Caroline, alone on the anniversary trip she meant to take with her husband, finds an old apothecary vial in the Thames mud.

A girl vanishes from an Adirondack summer camp, and the investigation ripples through the camp's wealthy families and the locals who serve them.

Belle da Costa Greene becomes J. P. Morgan's personal librarian, building his collection of rare manuscripts and art into a library that makes her one of the most powerful women in New York, while hiding that she is a Black woman passing as white.

Esme, a motherless girl, grows up under the sorting table of the Scriptorium in Oxford, where her father and other lexicographers are compiling the Oxford English Dictionary, and starts to keep the words they throw away.

Eva Abrams, a semi-retired Florida librarian, sees a newspaper photograph of a book stolen by the Nazis that she has not seen in sixty years, the book that holds the key to the papers she and a forger named Rémy made for Jewish children in occupied France.

In 2017 Marisol Ferrera travels from Miami to Cuba to scatter the ashes of her grandmother Elisa, who in 1958, as a sugar baron's daughter in Havana, fell in love with a young revolutionary.

A debutante, an East End girl and a shy puzzle-solver become codebreakers at Bletchley Park, then reunite on the eve of the 1947 royal wedding to unmask the traitor among them.

Nan O'Dea, the mistress of Archie Christie, tells her story of the eleven days in December 1926 when his wife, Agatha Christie, disappeared.

Alice Wright marries a handsome American to escape her stifling life in England, and in Baileyville, Kentucky, in 1937, she joins the Packhorse Library, riding into the Appalachian mountains with books under the lead of the fiercely independent Margery O'Hare.

In 1947 a pregnant American college girl searching for her missing cousin teams up with a bitter former spy who served in a network of women agents in occupied France during World War I.

When her mother stops answering the phone, Margot Lee, twenty-six, goes home to Koreatown in Los Angeles and finds her dead, and as she tries to find out what happened, the story of Mina's arrival in 1987 is told alongside hers.